a comparative study on vaccination pain in the methods of massage therapy and mothers’ breast feeding during injection of infants referring to navabsafavi health care center in isfahan

background: vaccination is one of the most common painful procedures in infants. the irreversible consequences due to pain experiences in infants are enormous. breast feeding and massage therapy methods are the non-drug methods of pain relief. therefore, this research aimed to compare the vaccination-related pain in infants who underwent massage therapy or breast feeding during injection. materials and methods: this study is a randomized clinical trial. ninety-six infants were allocated randomly and systematically to three groups (breast feeding, massage, and control groups). the study population comprised all infants, accompanied by their mothers, referring to one of the health centers in isfahan for vaccination of hepatitis b and dpt at 6 months of age and for mmr at 12 months of age. data gathering was done using questionnaire and checklist [neonatal infant pain scale (nips)]. data analysis was done using descriptive and inferential statistical methods with spss software. results: findings of the study showed that the three groups had no statistically significant difference in terms of demographic characteristics ( p > 0/05). the mean pain scores in the breast feeding group, massage therapy, and control group were 3.4, 3.9, and 4.8, respectively ( p < 0.05). then the least significant difference (lsd) post hoc test was performed. differences between the groups, i.e. massage therapy and breast feeding ( p = 0.041), breast feeding group and control ( p < 0.001), and massage therapy and control groups ( p = 0.002) were statistically significant. conclusion: considering the results of the study, it seems that breast feeding during vaccination has more analgesic effect than massage therapy. therefore, it is suggested as a noninvasive, safe, and accessible method without any side effects for reducing vaccination-related pain.